Pilot
Study 2: Study of Arthritis Chronic Pain Using Animal Models
Chronic diseases such as diabetic neuropathy, arthritis, or the joint-pain
episodes of sickle cell anemia, afflict disproportionately rural elderly
and rural minority populations and are vehicles of severe chronic pain.
Life-style patterns within these populations are known to be a major
contributor to their persistent chronic pain. As a coping and ameliorative
strategy for these ailments, life style changes have economic and medical
advantages over pharmacological palliation. This pilot project aims
to provide a basic-science resource for professionals serving such groups,
through studies of palliative and preventative life-style effects on
chronic pain in animal models. Such models are vital to addressing these
questions, since parallel human studies for obvious ethical reasons
are not possible. The health benefits of this work stem from the likelihood
of establishing nutritional or other environmental factors to be applied
in multi-factorial approaches to ameliorating chronic pain due to healthcare
disparities. (Ian Hentall PhD, Principal
Investigator)